Brief Report Rectal pH in Well and Unwell Infants
نویسندگان
چکیده
Prompt antibiotic treatment for infants with sepsis has the potential to save lives. A rectal formulation of an antibiotic could be used at a village level before referral to hospital. The development of such a preparation needs to take into account the rectal pH of infants that will affect drug partitioning and absorption. Rectal pH measurements were taken in 100 well and 45 unwell infants. We also measured rectal pH in 14 infants sequentially over the course of their illness. The mean rectal pH was 6.75 with no significant difference in well or unwell infants. The mean (95% CI) rectal pH of well neonates was significantly lower than that of older infants (>28 days): 6.47 (6.29–6.65) vs. 6.90 (6.68 to 7.12) p1⁄4 0.003.
منابع مشابه
Rectal pH in Well and Unwell Infants
Prompt antibiotic treatment for infants with sepsis has the potential to save lives. A rectal formulation of an antibiotic could be used at a village level before referral to hospital. The development of such a preparation needs to take into account the rectal pH of infants that will affect drug partitioning and absorption. Rectal pH measurements were taken in 100 well and 45 unwell infants. We...
متن کاملThe Clinical Presentation and Outcome of Infants with Nodular Lymphoid Hyperplasia: Experience with 34 Cases from Southern Iran
Background: Rectal bleeding is a relatively uncommon, but potentially important problem in early infancy. The common causes of fresh rectal bleeding in this age group are: bleeding diathesis (vit. K deficiency), infectious colitis, cow’s milk protein allergy and anal fissure. Nodular lymphoid hyperplasia (NLH) is another cause of prolonged fresh rectal bleeding in early infancy. Objective: To...
متن کاملOrbital Metastasis from Rectal Adenocarcinoma- Report of a Rare Case
Colorectal carcinoma is a common malignancy in India as well as in world. Inspite of its high metastasizing ability to various organs and lymph node, orbital metastasis is exceptional. Very few cases have been reported in the world literature. We report orbital metastasis in a case of moderately differentiated rectal adenocarcinoma in a 58-year male patient from India in 2015. We want to focus ...
متن کاملComparison between rectal administration of diazepam in solution and intravenous administration for management of convulsive disorders in infants and children
In order to compare rectal and intravenous(IV) administration of diazepam for management of convulsions,a prospective cross-sectional case-control study was conducted on 94 convulsive infants and children referring to the Emergency department of the university hospital No.1 in Kerman.all children were randomly divided into two groups.the patients were matched with regard to the cause,type,durat...
متن کاملUse of Foley Catheter Instead of Digital Rectal Examination for Detection of Gastrointestinal Bleeding in Infants and Children
A digital rectal examination is a highly important procedure carried out on infants and children during visits to the gastroenterology clinic, but is often accompanied with physiologic and psychologic trauma in patients, along with being diagnostically inaccurate in the results obtained from it. In order to avoid causing discomfort to the patients, and to improve the accuracy of the results obt...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012